158 - - clinical trial



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"Speaking of which, what were you talking about earlier with Mr. Meme, Mr. Barca?"

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"What you were talking about earlier? I wonder what it was."

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"You two were talking about experimenting to see if the treatment works or not. Are you sure you're not thinking of using living people as experimental material?

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"Of course, in order to confirm the effectiveness of a treatment that is currently being performed in the real world, you have to do it on actual sick people. I don't know what you're talking about.

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"Wow. Are you two really going to go that far? I'm afraid I can't help you with that. Human experimentation is a terrible thing.

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"That's a bad way to put it. It's a clinical trial. We're just taking data from real sick people and making them pay less for it. It's a win-win situation because you get the treatment at a lower cost."

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"...... Really? You don't concoct dubious medicines at night and force people to take them if they don't want to, do you, Mr. Barca?"

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"I would never do such a thing, Mr. Painter. Memes aside, I'm a real human being with a sane sensibility.

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"......Well, let's put it that way. So, you mean that you actually treat patients with diseases, and examine whether they are cured or not, and make it into data. Then I don't have to draw pictures, so it doesn't seem relevant to me."

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"No, you're right. No, that's right. We'll have you participate in the clinical trial, too, Mr. Painter. Some diseases may cause characteristic physical changes in the body, so I will ask you to describe them.

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"...... Oh, no. I've been a bit of a snake. Mr. Barca, I want to paint.

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"Don't worry. I'll let you paint as much as you want.

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"Ugh, I really don't know how I got into this mess. I never thought my dream life as a painter would turn out like this. ......"

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"I'm glad you're so happy, I'm glad you're crying too. Oh, and about the clinical trial, we're not just going to look at whether you're cured or not. I'm going to ask you to collect data as well, so please keep that in mind."

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"Oh, no? What are you going to do?

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"I've already explained this to Meme, but I'm thinking of doing a comparative study. That should give us a better idea of the effectiveness of the treatment.

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 The anatomical drawings are not yet complete.

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 However, Mr. Painter seems to be interested in clinical trials after the autopsy is completed.

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 Since we can't leave it to memes alone, let's involve Mr. Painter in the process now.

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 With this in mind, I decided to have a little talk with him now.

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 About the evaluation of the effectiveness of the treatment.

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 I don't know much about how to do it, but in my previous life, there was a lot of medical information on TV and so on.

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 I remember what I heard from them, and I have explained it to Meme.

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 That is, it is not accurate to simply treat a patient with a disease and discuss whether he/she is cured or not as a way to confirm the effectiveness of the treatment.

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 If the treatment actually cures the patient, then it is an effective treatment.

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 I once felt so when I saw it on TV.

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 However, it is said that there are actually cases in which a patient can be cured without any effect at all.

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 For example, if a person is treated by a professor of some medical school, many people may think "this will make me better" without any evidence.

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 Or, it is the same in the case of taking a medicine that is said to be effective for a disease.

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 Even if it is ineffective, a person may be cured only by his/her belief.

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 This is a phenomenon called the placebo effect.

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 Probably, there are many people in this world who are cured by this placebo effect, even though there are doctors who are not well versed in their own way of treatment.

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 Just saying that the body is cured after the treatment does not tell us whether the treatment was actually effective or not, or whether the placebo effect worked or not.

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 Therefore, it is necessary to verify the effect by comparison.

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 If you want to examine the effect of a drug, you need to examine the case of taking the drug you want to examine the effect of and the case of not taking the drug.

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 If they want to get better data, they sometimes give fake drugs that are neither poison nor medicine.

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 They divide patients with the same disease into two groups, and test to what extent the probability of cure is different or the same between those who take the drug and those who take the fake drug.

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 We will then compare the results of the two groups in a comparative study to ascertain the effectiveness of this world's treatment methods.

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 Well, in reality, more detailed procedures may be necessary, but since I am not familiar with such procedures, I will let it be enough.

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"Well, you mean to compare the group that actually does the treatment and the group that does not. Isn't that a pain in the ass?

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"Well, we're going to do clinical trials anyway, so let's at least do this. I don't want to end up talking about weapons ointment."

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"Weapons ointment? What's that?

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"It's a story about a wrong experimental method that proves the effectiveness of a wrong treatment and spreads."

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 Weapons ointment is a story from the Middle Ages of the last century.

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 In order to heal patients injured by weapons on the battlefield, ointment was applied not to the patient's body but to the weapon.

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 It is said that this method was tested for its effectiveness and was recognized as the most advanced treatment method at that time.

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 In a normal way, it is impossible for a human body to be healed by applying ointment to weapons.

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 But why was such a thing done at that time?

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 There was a reason.

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 In this story, the reason is that the way of experimentation at that time was wrong.

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 At that time, the rate of healing was higher when the ointment was applied to the weapon than when the ointment was applied to the patient's body.

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 Why did this happen?

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 It is because the ointments, or medicines of the time, were mixed with animal dung, mud, and other substances that are harmful to the human body.

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 In other words, if I understand this story correctly, it was better to put ointment on the weapon and let the body heal itself faster than to receive the common treatments of the medieval times.

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"Well, that's why I want to take the data in a way that is certain. Will you cooperate with me, Mr. Painter?

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"Well, from what I've heard, it doesn't sound like you're going to experiment on people just for the fun of it. I understand. I will cooperate with you, Mr. Barca.

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 It seems that Mr. Painter has been convinced and is willing to cooperate.

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 However, I wonder how much of an impact this clinical trial will really have.

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 The existence of such things as recovery magic is far from what I know.

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 There is a possibility that there is a magic that heals even if ointment is applied to a weapon.

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 It is not a meme, but I was a little excited before I started to see what kind of results I could get from the clinical trial.

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